Article

Polygenic scores for obstructive sleep apnea based on BMI-adjusted and -unadjusted genetic associations reveal pathways contributing to cardiovascular disease

2024-10-21

Abstract excerpt

<h4>Background</h4> Obstructive sleep apnea (OSA) is a heterogeneous disease, with obesity a significant risk factor via increased airway collapsibility, reduced lung volumes, and possibly body fat distribution. <h4>Methods</h4> Using race/ethnic diverse samples from the Million Veteran Program, FinnGen, TOPMed, All of Us (AoU), Geisinger’s MyCode, MGB Biobank, and the Human Phenotype Project (HPP), we developed,...

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Literature Corpus work: 7f8fb6d8-cd4d-5991-b082-e084014f49d3
DOI: 10.1101/2024.10.20.24315783

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