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Multiscale Spatial Transcriptomic Atlas of Human Basal Ganglia Cell-Type and Cellular Community Organization

2025-12-05

Abstract excerpt

<h4>SUMMARY</h4> We generated a multi-region, subcellular-resolution spatial transcriptomic atlas of the human basal ganglia by integrating MERFISH+ and Stereo-seq across four neurotypical donors. These datasets profiled ∼7 million cells spanning the caudate, putamen, nucleus accumbens, and globus pallidus, resolving 60 transcriptionally distinct cell types. We show region-selective, molecular and spatial diversi...

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Identifiers and source

Literature Corpus work
6cc27507-e24a-5eac-9402-f29f1988a493
DOI
10.64898/2025.12.02.691876
Open publication

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Multiscale Spatial Transcriptomic Atlas of Human Basal Ganglia Cell-Type and Cellular Community OrganizationDOI 10.64898/2025.12.02.691876
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