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Article

Combination of QTL and GWAS to uncover the role of phosphodiesterases in ischemic heart disease

2023-09-25

Abstract excerpt

<h4>Background</h4> Phosphodiesterases (PDEs) are regarded as important therapeutic targets for multiple diseases, and the cardiovascular benefits of several PDE inhibitors have received extensive interests. <h4>Objectives</h4> To explore the relationship between genetically-predicted PDEs and ischemia heart disease via drug target Mendelian Randomization (MR) approach. <h4>Methods</h4> The expression of genes enc...

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Literature Corpus work
6c8e8e1d-545b-523e-a44d-2cf29421afa8
DOI
10.1101/2023.09.24.23296052
Open publication

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Combination of QTL and GWAS to uncover the role of phosphodiesterases in ischemic heart diseaseDOI 10.1101/2023.09.24.23296052
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