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Article

Disconnect Between Genes Associated With Ischemic Heart Disease and Targets of Ischemic Heart Disease Treatments.

EBioMedicine - 1 Feb 2018

Schooling C M, Huang J V, Zhao J V, Kwok M K, Au Yeung S L, Lin S L

Abstract excerpt

BACKGROUND: Development of pharmacological treatments to mitigate ischemic heart disease (IHD) has encompassed disappointing results and expensive failures, which has discouraged investment in new approaches to prevention and control. New treatments are most likely to be successful if they act on genetically validated targets. We assessed whether existing pharmacological treatments for IHD reduction are acting on...

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Source

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Identifiers

PMID: 29396305
DOI: 10.1016/j.ebiom.2018.01.015
PMCID: PMC5835561

Genes

CETP
CXCL12
EDNRA
LPL
LRP1
PCSK9
PLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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