Article

Blood-based epigenome-wide analyses on the prevalence and incidence of nineteen common disease states

2023-01-11

Abstract excerpt

<h4>Background</h4> Blood DNA methylation can inform us about the biological mechanisms that underlie common disease states. Previous epigenome-wide analyses of common diseases often focus solely on the prevalence or incidence of individual conditions and rely on small sample sizes, which may limit power to discover disease-associated loci. <h4>Results</h4> We conduct blood-based epigenome-wide association studies...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6c72912a-9535-507b-942b-1c41bee3965b
DOI: 10.1101/2023.01.10.23284387

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Blood-based epigenome-wide analyses on the prevalence and incidence of nineteen common disease statesDOI 10.1101/2023.01.10.23284387Read

Systematic classification of shared components of genetic risk for common human diseasesSemantic proximity Read

Comparison of phenomic profiles in the All of Us Research Program against the US general population and the UK Biobank.Semantic proximity Read

A meta-analysis of immune cell fractions at high resolution reveals novel associations with common phenotypes and health outcomesSemantic proximity Read

Genomic and phenomic insights from an atlas of genetic effects on DNA methylationSemantic proximity Read

Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traitsSemantic proximity Read

Shared genomic architecture between COVID-19 severity and numerous clinical and physiologic parameters revealed by LD score regression analysis.Semantic proximity Read

Exploiting shared omics architecture and causal association between complex traits and COVID-19Semantic proximity Read

Human panepigenome represents epigenomic diversitySemantic proximity Read

Distinct Co-Methylation Patterns in African and European Populations and Their Genetic AssociationsSemantic proximity Read

Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysisSemantic proximity Read

Phenome-Wide Association Study of Pre-Cancer Diagnosis Electronic Health Records Identifies Risk and Inverse Associations in the All of Us Research ProgramSemantic proximity Read

The EWAS Catalog: a database of epigenome-wide association studiesSemantic proximity Read