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Article

Shared genomic architecture between COVID-19 severity and numerous clinical and physiologic parameters revealed by LD score regression analysis.

Scientific reports - 3 Feb 2022

Byun Jinyoung, Han Younghun, Walsh Kyle M, Park Amy S, Bondy Melissa L, Amos Christopher I

Abstract excerpt

The COVID-19 pandemic has produced broad clinical manifestations, from asymptomatic infection to hospitalization and death. Despite progress from genomic and clinical epidemiology research, risk factors for developing severe COVID-19 are incompletely understood and identification of modifiable risk factors is desperately needed. We conducted linkage disequilibrium score regression (LDSR) analysis to estimate...

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Identifiers

PMID: 35115602
DOI: 10.1038/s41598-022-05832-5
PMCID: PMC8814062

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