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Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis

10 May 2022

Abstract excerpt

Abstract Rationale Methylation integrates factors present at birth and modifiable across the lifespan that can influence pulmonary function. Studies are limited in scope and replication. Objectives To conduct large-scale epigenome-wide meta-analyses of blood DNA methylation and pulmonary function. Methods Twelve cohorts analyzed associations of methylation at cytosine-phosphate-guanine probes (CpGs), using...

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PMID: 35536696
DOI: 10.1164/rccm.202108-1907oc

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