Article

Evaluating lipid-lowering drug targets for Parkinson disease prevention with Mendelian randomization

2020-05-08

Abstract excerpt

<h4>Objective</h4> To examine whether long-term exposure to statins and other lipid-lowering drugs may affect PD risk – either beneficially or adversely – using Mendelian randomization (MR). <h4>Methods</h4> MR analyses were based on variants in genes encoding the targets of several approved or emerging drug classes that reduce circulating low-density lipoprotein cholesterol (LDL-C) or triglycerides. Variants were...

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Literature Corpus work: 6c43d3b5-58a6-5a26-8bd7-ff94a461630b
DOI: 10.1101/2020.05.04.20090142

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