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Article

Systematic genome-wide Mendelian randomization reveals the causal links between miRNAs and Parkinson’s disease

3 May 2024

Abstract excerpt

Background MicroRNAs (miRNAs) have pivotal roles in gene regulation. Circulating miRNAs have been developed as novel candidate non-invasive biomarkers for diagnosis, prognosis, and treatment response for diseases. However, miRNAs that have causal effects on Parkinson’s Disease (PD) remain largely unknown. To investigate the causal relationships between miRNAs and PD, here we conduct a Mendelian randomization (MR)...

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Identifiers

PMID: 38765669
DOI: 10.3389/fnins.2024.1385675

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