Article
The Parkinson's Disease Mendelian Randomization Research Portal.
Movement disorders : official journal of the Movement Disorder Society - 1 Dec 2019
Noyce Alastair J, Bandres-Ciga Sara, Kim Jonggeol, Heilbron Karl, Kia Demis, Hemani Gibran, Xue Angli, Lawlor Debbie A, Smith George Davey, Duran Raquel, Gan-Or Ziv, Blauwendraat Cornelis, Gibbs J Raphael, Hinds David A, Yang Jian, Visscher Peter, Cuzick Jack, Morris Huw, Hardy John, Wood Nicholas W, Nalls Mike A, Singleton Andrew B
Abstract excerpt
BACKGROUND: Mendelian randomization is a method for exploring observational associations to find evidence of causality. OBJECTIVE: To apply Mendelian randomization between risk factors/phenotypic traits (exposures) and PD in a large, unbiased manner, and to create a public resource for research. METHODS: We used two-sample Mendelian randomization in which the summary statistics relating to single-nucleotide...
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