Article

In silico construction and evaluation of anti-EGFR ScFv and IFN-β fusion protein as a novel immunocytokine for the treatment of HER1 positive breast cancer

2023-03-23

Abstract excerpt

Context Human epidermal growth factor receptor 1 (HER1) positive breast cancer is characterized by overexpression of the HER1 receptor protein on cancer cells leading to aggressive disease and treatment resistance. Computational design can efficiently create immunocytokine that specifically target cancer cell antigens and modulate the immune response, making them a promising treatment for HER1-positive breast canc...

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Literature Corpus work: 6c3b67a1-6c43-5662-a5c6-c7d88413b92d
DOI: 10.21203/rs.3.rs-2711460/v1

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