Article

In Silico and In Vitro Investigations On Mutated IFNβ-scFv Against Human Collagen Type II

2021-11-09

Abstract excerpt

<title>Abstract</title> <p>Current medications for rheumatoid arthritis (RA), a common synovial autoimmune disease, are associated with adverse effects. Interestingly, interferon beta (IFNβ), effective in multiple sclerosis (MS) treatment, also can help decreasing articular destruction in RA. Here, a novel fusion protein was introduced containing human mutated IFNβ (with mutations in 27th and 101th residues; IFNβ...

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Literature Corpus work: 3a4b1285-ea22-584b-a0cb-1355211066cd
DOI: 10.21203/rs.3.rs-987486/v1

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