Article

Metformin preconditioning protects against myocardial stunning and preserves mitochondrial dynamics and protein translation in a mouse model of cardiac arrest

2021-08-25

Abstract excerpt

Cardiac arrest (CA) causes high mortality due to multi-system organ damage attributable to ischemia-reperfusion injury. Recent work in our group found that among diabetic patients who experienced cardiac arrest, those taking metformin had less evidence of cardiac and renal damage after cardiac arrest when compared to those not taking metformin. To investigate the potential for metformin to impact cardiac arrest ou...

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Literature Corpus work: 6c289e50-f146-5955-9ba9-eb8cf651f2e8
DOI: 10.1101/2021.08.24.457506

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