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Autophagic Flux Impairment Exacerbates Myocardial Ischemia-Reperfusion Injury in Experimental Diabetes Through Atg5/LAMP2 Cleavage by Calpains

2020-08-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: is a chronic metabolic disease characterized by hyperglycemia, which has negative effects on cardiac revascularization in patients with coronary artery disease (CAD). <bold>Methods:</bold> This study focused on the role of autophagic flux in regulating susceptibility of STZ-induced diabetic heart to ischemia-reperfusion (I/R) injury. We established STZ-induced d...

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Literature Corpus work
ff4284b1-e971-52d7-b582-39ff19286fb1
DOI
10.21203/rs.3.rs-42392/v1
Open publication

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Autophagic Flux Impairment Exacerbates Myocardial Ischemia-Reperfusion Injury in Experimental Diabetes Through Atg5/LAMP2 Cleavage by CalpainsDOI 10.21203/rs.3.rs-42392/v1
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