Article

Plasma membrane folding enables constant surface area-to-volume ratio in growing mammalian cells

2024-07-04

Abstract excerpt

<h4>ABSTRACT</h4> All cells are subject to geometric constraints, including the surface area-to-volume (SA/V) ratio, which can limit nutrient uptake, maximum cell size, and cell shape changes. Like the SA/V ratio of a sphere, it is generally assumed that the SA/V ratio of cells decreases as cell size increases. However, the structural complexity of the plasma membrane makes studies of the surface area challenging...

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Literature Corpus work: 6c1916cf-6271-5cfa-965b-65680f999c4e
DOI: 10.1101/2024.07.02.601447

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