Article
Physical forces and non linear dynamics mould fractal cell shape: quantitative morphological parameters and cell phenotype.
Histology and histopathology - 1 Feb 2013
Bizzarri M, Pasqualato A, Cucina A, Pasta V
Abstract excerpt
Cell shape is mainly determined by biophysical constraints, interacting according to non-linear dynamics upon the basic units provided by the genome. In turn, the specific configuration a cell acquires plays a fundamental, permissive role in modulating gene expression and many other complex biological functions. Cell shape is tightly connected to cell activity and can be considered the most critical determinant...
Topics
- Animals
- Biophysical Phenomena
- Cell Shape
- Cytoskeleton
- Fractals
- Humans
- Models, Biological
- Neoplasms
- Nonlinear Dynamics
- Phenotype
