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Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in <i>Aedes aegypti</i> mosquitoes

2018-07-09

Abstract excerpt

Dengue virus (DENV), an arthropod-borne (“arbovirus”) virus causing a range of human maladies ranging from self-limiting dengue fever to the life-threatening dengue shock syndrome, proliferates well in two different taxa of the Animal Kingdom, mosquitoes and primates. Unexpectedly, mosquitoes and primates have distinct preferences when expressing their genes by translation, e.g. members of these taxa show taxonom...

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Literature Corpus work
6c072a59-a12c-55d8-b1e0-63585d2d3430
DOI
10.1101/365189
Open publication

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