Article

Dengue virus preferentially uses human and mosquito non-optimal codons

2023-06-14

Abstract excerpt

Codon optimality refers to the effect codon composition has on messenger RNA (mRNA) stability and translation level and implies that synonymous codons are not silent from a regulatory point of view. Here, we investigated the adaptation of virus genomes to the host optimality code using mosquito-borne dengue virus (DENV) as a model. We defined which codons are associated with unstable and stable (non-optimal and op...

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Literature Corpus work: 3b2446d5-cd2b-5b59-b690-8658ed9a1553
DOI: 10.1101/2023.06.14.544804

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