Article

The landscape of selection in 551 Esophageal Adenocarcinomas defines genomic biomarkers for the clinic

2018-04-28

Abstract excerpt

Esophageal Adenocarcinoma (EAC) is a poor prognosis cancer type with rapidly rising incidence. Our understanding of genetic events which drive EAC development is limited and there are few molecular biomarkers for prognostication or therapeutics. We have accumulated a cohort of 551 genomically characterised EACs (73% WGS and 27% WES) with clinical annotation and matched RNA-seq. Using a variety of driver gene detec...

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Literature Corpus work: 6be73cdf-a190-5a27-b0d0-c89ddd6b2aaa
DOI: 10.1101/310029

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