Article
An Old Story Retold: Loss of G1 Control Defines A Distinct Genomic Subtype of Esophageal Squamous Cell Carcinoma.
Genomics, proteomics & bioinformatics - 1 Aug 2015
Wang Qiyan, Bai Jian, Abliz Amir, Liu Ying, Gong Kenan, Li Jingjing, Shi Wenjie, Pan Yaqi, Liu Fangfang, Lai Shujuan, Yang Haijun, Lu Changdong, Zhang Lixin, Chen Wei, Xu Ruiping, Cai Hong, Ke Yang, Zeng Changqing
Abstract excerpt
Esophageal squamous cell carcinoma (ESCC) has a high mortality rate. To determine the molecular basis of ESCC development, this study sought to identify characteristic genome-wide alterations in ESCC, including exonic mutations and structural alterations. The clinical implications of these genetic alterations were also analyzed. Exome sequencing and verification were performed for nine pairs of ESCC and the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.