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Article

Whole-genome sequencing of nine esophageal adenocarcinoma cell lines

10 Jun 2016

Abstract excerpt

Esophageal adenocarcinoma (EAC) is highly mutated and molecularly heterogeneous. The number of cell lines available for study is limited and their genome has been only partially characterized. The availability of an accurate annotation of their mutational landscape is crucial for accurate experimental design and correct interpretation of genotype-phenotype findings. We performed high coverage, paired end whole...

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PMID: 27594985
DOI: 10.12688/f1000research.7033.1

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