Article

Effects of polygenic risk for suicide attempt and risky behavior on brain structure in young people with familial risk of bipolar disorder

2021-09-14

Abstract excerpt

<h4>Aims</h4> Bipolar Disorder (BD) is associated with a 20-30 fold increased suicide risk compared to the general population. First-degree relatives of BD patients show inflated rates of psychopathology including suicidal behaviors. As reliable biomarkers of suicide attempts (SA) are lacking, we examined associations between suicide-related polygenic risk scores (PRS) – a quantitative index of genomic risk – and...

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Literature Corpus work: 6bce8ae5-a7e8-59e0-ae2c-d9faff4a75c5
DOI: 10.1101/2021.09.06.21262817

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