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Genetic Links Between Subcortical Brain Morphometry and Suicide Attempt Risk in Children and Adults.

Human brain mapping - 1 May 2025

Ceja Zuriel, García-Marín Luis M, Hung I-Tzu, Medland Sarah E, Edwards Alexis C, Rentería Miguel E, Rabinowitz Jill A

Abstract excerpt

Genome-wide association studies (GWAS) have uncovered genetic variants associated with suicide attempt (SA) risk and regional brain volumes (RBVs). However, the extent of their genetic overlap remains unclear. To address this, we investigated whether the genetic architecture of SA and various RBVs (i.e., caudate nucleus, hippocampus, brainstem, ventral diencephalon, thalamus, globus pallidus, putamen, nucleus...

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Identifiers

PMID: 40364472
DOI: 10.1002/hbm.70220
PMCID: PMC12075092

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