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Article

Next-generation bNAbs for HIV-1 cure strategies

28 Dec 2023

Abstract excerpt

Despite the ability to suppress viral replication using anti-retroviral therapy (ART), HIV-1 remains a global public health problem. Curative strategies for HIV-1 have to target and eradicate latently infected cells across the body, i.e. the viral reservoir. Broadly neutralizing antibodies (bNAbs) targeting the HIV-1 envelope glycoprotein (Env) have the capacity to neutralize virions and bind to infected cells to...

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PMID: 38158130
DOI: 10.1016/j.antiviral.2023.105788

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