Article

Peptide signaling in the paraventricular thalamus contributes to disrupted adult reward behaviors after early-life adversity

2026-04-02

Abstract excerpt

Early-life adversity (ELA) is strongly linked to emotional disorders characterized by dysregulated reward behaviors including diminished motivation for and enjoyment of rewards (anhedonia). However, how transient ELA leads to enduring disruptions of reward behaviors remains unclear. Using activity-dependent genetic labeling during ELA, we previously found that the paraventricular thalamic nucleus (PVT) uniquely d...

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Literature Corpus work: 6bca4b9c-63bf-570a-bcaf-2be3d80cefba
DOI: 10.64898/2026.03.31.715695

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