Article

Effects of early life adversity on immediate early gene expression: systematic review and 3-level meta-analysis of rodent studies

2021-06-07

Abstract excerpt

Early-life adversity (ELA) causes long-lasting structural and functional changes to the brain, rendering affected individuals vulnerable to the development of psychopathologies later in life. Immediate-early genes (IEGs) provide a potential marker for the observed alterations, bridging the gap between activity-regulated transcription and long-lasting effects on brain structure and function. Several heterogeneous s...

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Literature Corpus work: 48cd0166-272f-515c-a742-6964848fd75c
DOI: 10.1101/2021.06.07.447369

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