Article
Spatially-resolved molecular sex differences at single cell resolution in the adult human ventromedial and arcuate hypothalamus
2024-12-09
Abstract excerpt
The hypothalamus contains multiple regions, including the ventromedial hypothalamus (VMH) and arcuate (ARC), which are responsible for sex-differentiated functions such as endocrine signaling, metabolism, and reproductive behaviors. While molecular, anatomic, and sex-differentiated features of rodent hypothalamus are well-established, much less is known about these regions in humans. Here we provide a spatially-re...
Topics
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- Adipose Tissue and Metabolism
- Cognitive Abilities and Testing
- Epigenetics and DNA Methylation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hypothalamic control of reproductive hormones
- Plant Reproductive Biology
- Regulation of Appetite and Obesity
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- ba54f7be-e549-5b31-b0c6-4a1e8c6bd68a
- DOI
- 10.1101/2024.12.07.627362