Article

Lactational transfer of synthetic oxytocin and sex-specific suppression of neurodevelopmental risk gene networks in the rat prefrontal cortex

2026-05-22

Abstract excerpt

Autism spectrum disorder and related neurodevelopmental disorders (NDDs) affect males at two-to-four times the rate of females, yet the environmental contributors to this sex-differentiated vulnerability remain poorly understood. Here, using a clinically translatable postpartum rat model, we show that synthetic oxytocin (OT) administered for postpartum hemorrhage (PPH) prophylaxis (‘PPH-OT’), a universally adminis...

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Literature Corpus work: 8a9dd833-e813-58d5-afac-c3577ef1e7f0
DOI: 10.64898/2026.05.19.726042

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