Article
Multi-polygenic scores in psychiatry: from disorder-specific to transdiagnostic perspectives
2022-05-31
Abstract excerpt
The dense co-occurrence of psychiatric disorders questions the categorical classification tradition and motivates efforts to establish dimensional constructs with neurobiological foundations that transcend diagnostic boundaries. In this study, we examined the genetic liability for eight major psychiatric disorder phenotypes under both a disorder-specific and a transdiagnostic framework. In a deeply-phenotyped samp...
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Identifiers and source
- Literature Corpus work
- 6bc6a41a-9a3a-59a6-b136-4b5a7acd551d
- DOI
- 10.1101/2022.05.30.22275563