Article

Trim-Away in adult animals through Nano-ERASER and its application in cancer therapy

2023-01-17

Abstract excerpt

Trim-Away is a versatile intracellular protein degradation pathway that has been extensively explored in vitro . However, the in vivo application of Trim-Away is limited at oocyte and zygote stages due to the lack of an in vivo practical approach for intracellular antibody delivery. To broaden the application of Trim-Away, especially for clinical use, we developed a nanogel-based Nano-ERASER system. Here, we demon...

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Literature Corpus work: 6ba97511-a972-5e8b-bd96-768890a20690
DOI: 10.21203/rs.3.rs-2298306/v1

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