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Nanoparticle-mediated delivery of peptide-based degraders enables targeted protein degradation

2024-05-22

Abstract excerpt

<title>Abstract</title> <p>The development of small molecule-based degraders against intracellular protein targets is a rapidly growing field that is hindered by the limited availability of high-quality small molecule ligands that bind to the target of interest. Despite the feasibility of designing peptide ligands against any protein target, peptide-based degraders still face significant obstacles such as limited...

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Literature Corpus work
c37f39ad-7f6e-507a-990d-a71471aa5b13
DOI
10.21203/rs.3.rs-3797623/v1
Open publication

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Nanoparticle-mediated delivery of peptide-based degraders enables targeted protein degradationDOI 10.21203/rs.3.rs-3797623/v1
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