Article
AI-driven discovery and engineering of human endogenous nanocage proteins for mRNA delivery
2026-02-09
Abstract excerpt
Safe and effective gene delivery remains a central challenge for therapeutic applications. While non-viral and viral vectors have enabled substantial progress, their reliance on non-human components often triggers immune responses, limiting their use in chronic treatments. Here, we developed DeepDelivery, an artificial intelligence-driven platform to repurpose human proteins for mRNA delivery. An unbiased screenin...
Topics
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- Advanced Biosensing Techniques and Applications
- CAR-T cell therapy research
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
- Viral Infectious Diseases and Gene Expression in Insects
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- 96a5c253-150f-5c6a-8b65-a2d2dd81fc91
- DOI
- 10.64898/2026.02.07.704552