Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mapping of host-parasite-microbiome interactions reveals metabolic determinants of tropism and tolerance in Chagas disease

22 Jul 2020

Abstract excerpt

protozoa, presenting with cardiomyopathy, megaesophagus, and/or megacolon. To determine the mechanisms of gastrointestinal (GI) CD tissue tropism, we systematically characterized the spatial localization of infection-induced metabolic and microbiome alterations, in a mouse model of CD. Notably, the impact of the transition between acute and persistent infection differed between tissue sites, with sustained...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insect symbiosis and bacterial influences
Share to Parasites and Host Interactions
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32766448
DOI: 10.1126/sciadv.aaz2015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mapping of host-parasite-microbiome interactions reveals metabolic determinants of tropism and tolerance in Chagas diseasePMID 32766448Read ↗

Spatially-divergent metabolic impact of experimental toxoplasmosis: immunological and microbial correlatesSemantic proximity Read ↗

Microbiome Alterations Driven by <i>Trypanosoma cruzi</i> Infection in Two Disjunctive Murine ModelsSemantic proximity Read ↗

Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolomeSemantic proximity Read ↗

The Association Between Prevotella copri and Advanced Fibrosis in the Progression of Metabolic Dysfunction-Associated Steatotic Liver DiseaseSemantic proximity Read ↗

Gut Microbiota and Mitochondria: Health and Pathophysiological Aspects of Long COVIDSemantic proximity Read ↗

Cardiac and Digestive Forms of Chagas Disease: An Update on Pathogenesis, Genetics, and Therapeutic TargetsSemantic proximity Read ↗

Gut Microbial Perturbation and Host Response Induces Redox Pathway Upregulation along the Gut-liver Axis during Giardiasis in C57BL/6J Mouse ModelSemantic proximity Read ↗

Single-Cell Mass Spectrometry Enables Insight into Heterogeneity in Infectious DiseaseSemantic proximity Read ↗

Time resolved multi-omics reveals diverse metabolic strategies of <i>Salmonella</i> during diet-induced inflammationSemantic proximity Read ↗

Persistent biofluid small molecule alterations induced by <i>Trypanosoma cruzi</i> infection are not restored by antiparasitic treatmentSemantic proximity Read ↗

Inhibition of systemic mammalian metabolism by carnitine mimics from the gut microbiotaSemantic proximity Read ↗

β-catenin driven innate and metabolic reprograming in macrophages fuel T-cells dependent inflammation in Toxoplasma gondii infection: implications for therapeutic interventionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.