Article

CD16a<sup>high</sup> NK cell infiltration and spatial relationships with T cells and macrophages can predict improved progression-free survival in high grade ovarian cancer

2021-06-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> High grade serous cancer (HGSC) remains a highly fatal malignancy with less than 50% of patients surviving 5 years after diagnosis. Despite its high mutational burden, HGSC is relatively refractory to checkpoint immunotherapy, suggesting that additional features of the cancer and its interactions with the immune system remain to be understood. Natural killer (NK) cells may con...

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Literature Corpus work: 6b352e2a-bd93-591c-a1bb-22d36a1f12ac
DOI: 10.1101/2021.06.08.21258566

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