Article

A TEMPORAL MODEL OF TUMOR-IMMUNE DYNAMICS IN HIGH GRADE SEROUS OVARIAN CANCER

2024-10-24

Abstract excerpt

<h4>ABSTRACT</h4> Patients with high-grade serous ovarian cancer (HGSOC) typically present with widespread metastasis, obscuring a temporal understanding of tumor-immune dynamics. We performed multi-site global proteomics and matched immunohistochemistry (IHC) of CD4+ and CD8+ tumor infiltrating lymphocytes (TILs) in patient samples. The protein expression profiles were ordered by pseudotime, recapitulating metas...

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Literature Corpus work: fa631bd0-18b5-5ea4-80bc-614035470ee0
DOI: 10.1101/2024.10.21.619446

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