Article

Convergent evolution of “genome guardian” functions in a parasite-specific <i>p53</i> homolog

2021-11-28

Abstract excerpt

<h4>Significance</h4> P53 is a widely studied tumor suppressor that is found throughout metazoans, including invertebrates that do not develop malignancies. The prevailing theory for why this is the case is that P53 originally evolved to protect the germline of early metazoans from genotoxic stress such as UV radiation. In this study, we examine the function of two P53 homologs in the parasitic flatworm Schistos...

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Literature Corpus work: 6afcabef-1575-5e58-a641-acc0d8c1359a
DOI: 10.1101/2021.11.28.470261

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