Article
Genetics of neurodegenerative diseases: an overview.
Handbook of clinical neurology - 1 Jan 2017
Pihlstrøm Lasse, Wiethoff Sarah, Houlden Henry
Abstract excerpt
Genetic factors are central to the etiology of neurodegeneration, both as monogenic causes of heritable disease and as modifiers of susceptibility to complex, sporadic disorders. Over the last two decades, the identification of disease genes and risk loci has led to some of the greatest advances in medicine and invaluable insights into pathogenic mechanisms and disease pathways. Large-scale research efforts,...
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