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Article

Assessment of genetic risk for improved clinical-neuropathological correlations.

Acta neuropathologica communications - 10 Sept 2020

Spencer Barbara E, Jennings Robin G, Fan Chun C, Brewer James B

Abstract excerpt

In the clinical diagnosis of dementia with Lewy bodies, distinction from Alzheimer's disease is suboptimal and complicated by shared genetic risk factors and frequent co-pathology. In the present study we tested the ability of polygenic scores for Alzheimer's disease, dementia with Lewy bodies, and Parkinson's disease to differentiate individuals in a 2713-participant, pathologically defined sample. A dementia...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32912321
DOI: 10.1186/s40478-020-01033-1
PMCID: PMC7488152

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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