Article

A novel lncRNA PROCA11 regulates cell plasticity in response to androgen deprivation of prostate cancer cells

2023-08-08

Abstract excerpt

Long non-coding RNAs (lncRNAs) represent vast and yet poorly characterized family of genes that can fine tune cellular plasticity, thereby allowing the emergence of aggressive therapy-resistant and metastatic cancers. Androgen deprivation therapies (ADT) are commonly used to treat prostate cancer by inactivating the Androgen Receptor (AR). However, castration-resistant prostate cancer (CRPC) with neuroendocrine su...

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Literature Corpus work: 6aebbbf4-12ca-517a-a6fb-8846bfc3d8e4
DOI: 10.1101/2023.08.07.552355

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