Article

Alterations in Nutrient Availability in the Lungs During <i>Streptococcus pneumoniae</i> -Induced Pneumonia

2025-07-14

Abstract excerpt

Streptococcus pneumoniae is a leading cause of pneumonia. Importantly, the extent and impact of changes in the infected airway on bacterial nutrient availability and gene expression are not known. Utilizing untargeted UPLC-ESI-MS/MS metabolomics, we comprehensively characterized the metabolic landscape in the airway across early, mid, and severe stages of pneumococcal pneumonia. This revealed that dynamic shifts i...

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Literature Corpus work: 6a90547c-e9d3-584e-a3bd-71c0611fe200
DOI: 10.1101/2025.07.14.664699

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