Article

Comprehensive Genomic Characterization of Breast Tumors with BRCA1 and BRCA2 Mutations

2018-09-05

Abstract excerpt

<h4>Background</h4> Germline mutations in the BRCA1 and BRCA2 genes predispose carriers to breast and ovarian cancer, and there remains a need to identify the specific genomic mechanisms by which cancer evolves in these patients. Here we present a systematic genomic analysis of breast tumors with BRCA1 and BRCA2 mutations. <h4>Methods</h4> We analyzed genomic data from breast tumors, with a focus on comparing tu...

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Literature Corpus work: 6a53b8d9-5325-50b5-8dc4-122d56533f3f
DOI: 10.1101/409813

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