Article

Transcriptome stability profiling using 5’-bromouridine IP chase (BRIC-seq) identifies novel and functional microRNA targets in human melanoma cells

2019-02-20

Abstract excerpt

<h4>ABSTRACT</h4> RNA half-life is closely related to its cellular physiological function, so stability determinants may have regulatory functions. Micro(mi)RNAs have primarily been studied with respect to post-transcriptional mRNA regulation and target degradation. Here we study the impact of the tumor suppressive melanoma miRNA miR-211 on transcriptome stability and phenotype in the non-pigmented melanoma cell...

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Literature Corpus work: 6a25ad02-b2cd-516f-b2f5-9af51cc6b6d3
DOI: 10.1101/555540

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