Article
Non-coding RNA profiling in BRAFV600E-mutant cutaneous melanoma before and after Spry1 depletion.
Scientific data - 2 Sept 2025
Lamberti Jessica, Memoli Domenico, Montico Barbara, Silvestro Francesco, Guerrieri Roberto, Colizzi Francesca, Weisz Alessandro, Salvati Annamaria, Fratta Elisabetta, Nassa Giovanni
Abstract excerpt
Cutaneous melanoma (CM), with a continuously rising incidence worldwide, represents the most aggressive type of skin cancer, and it leads to the majority of skin cancer-related deaths. Approximately 50% of CM carry the activating BRAFV600 mutation and, although BRAF inhibitors have demonstrated clinical efficacy, most patients often develop early resistance to treatment. Aberrant expression of non-coding RNAs...
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