Back to search

Article

The genomic and evolutionary landscapes of anaplastic thyroid carcinoma

2023-04-11

Abstract excerpt

Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are unknown. We sequenced tumor DNA from 329 regions of thyroid cancer, including 213 from patients with primary anaplastic thyroid carcinomas and multi-region whole-genome sequencing. Anaplastic thyroid carcinomas have a higher burden of m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6a05ccce-fb43-54c2-a41c-20f9800e3783
DOI
10.1101/2023.04.10.23288365
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The genomic and evolutionary landscapes of anaplastic thyroid carcinomaDOI 10.1101/2023.04.10.23288365
The genomic and evolutionary landscapes of anaplastic thyroid carcinoma.Semantic proximity
Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers.Semantic proximity
Identification of Targetable Lesions in Anaplastic Thyroid Cancer by Genome ProfilingSemantic proximity
Clonal evolution analysis of paired anaplastic and well‐differentiated thyroid carcinomas reveals shared common ancestorSemantic proximity
The genomic and transcriptomic landscape of anaplastic thyroid cancer: implications for therapy.Semantic proximity
Genomic Alterations of Anaplastic Thyroid Carcinoma Detected by Targeted Massive Parallel Sequencing in a BRAF(V600E) Mutation-Prevalent Area.Semantic proximity
Unique mutation patterns in anaplastic thyroid cancer identified by comprehensive genomic profilingSemantic proximity
The Genomic Landscape of Thyroid Cancer Tumourigenesis and Implications for Immunotherapy.Semantic proximity
Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing.Semantic proximity
Pan-Genomic Sequencing Reveals Actionable CDKN2A/2B Deletions and Kataegis in Anaplastic Thyroid CarcinomaSemantic proximity
Recent Progress of Genome Study for Anaplastic Thyroid CancerSemantic proximity
Genomic Landscape of poorly Differentiated and Anaplastic Thyroid Carcinoma.Semantic proximity
Select a neighboring publication to make it the new centre.