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Article

Genomic Landscape of poorly Differentiated and Anaplastic Thyroid Carcinoma.

Endocrine pathology - 1 Sept 2016

Xu Bin, Ghossein Ronald

Abstract excerpt

Poorly differentiated thyroid carcinoma (PDTC) and anaplastic thyroid carcinoma (ATC) are aggressive thyroid tumors associated with a high mortality rate of 38-57 % and almost 100 % respectively. Several recent studies utilizing next generation sequencing techniques have shed lights on the molecular pathogenesis of these tumors, providing evidence to support a stepwise tumoral progression from well-differentiated...

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Identifiers

PMID: 27372303
DOI: 10.1007/s12022-016-9445-4

Genes

BRAF
PTEN
TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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