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Article

Genomic Alterations of Anaplastic Thyroid Carcinoma Detected by Targeted Massive Parallel Sequencing in a BRAF(V600E) Mutation-Prevalent Area.

Thyroid : official journal of the American Thyroid Association - 1 May 2016

Jeon Min Ji, Chun Sung-Min, Kim Deokhoon, Kwon Hyemi, Jang Eun Kyung, Kim Tae Yong, Kim Won Bae, Shong Young Kee, Jang Se Jin, Song Dong Eun, Kim Won Gu

Abstract excerpt

BACKGROUND: Anaplastic thyroid carcinoma (ATC), the most aggressive type of thyroid cancer, has no effective therapy. Due to its dismal prognosis, it is vital to understand the genetic alterations of ATC and identify effective molecular targets. Targeted next-generation sequencing was performed to investigate the mutational profile of ATC using a massive parallel sequencing approach. METHODS: DNA from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 26980298
DOI: 10.1089/thy.2015.0506

Genes

BRAF
RASAL1
KRAS
PKHD1
PTEN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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