Article
Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers.
Endocrinology and metabolism (Seoul, Korea) - 1 Mar 2020
Yoo Seong Keun, Song Young Shin, Park Young Joo, Seo Jeong Sun
Abstract excerpt
Anaplastic thyroid cancer (ATC) is a lethal human cancer with a 5-year survival rate of less than 10%. Recently, its genomic and transcriptomic characteristics have been extensively elucidated over 5 years owing to advance in high throughput sequencing. These efforts have extended molecular understandings into the progression mechanisms and therapeutic vulnerabilities of aggressive thyroid cancers. In this...
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