Article
Differential Song Deficits after Lentivirus-Mediated Knockdown of FoxP1, FoxP2, or FoxP4 in Area X of Juvenile Zebra Finches.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 4 Dec 2019
Norton Philipp, Barschke Peggy, Scharff Constance, Mendoza Ezequiel
Abstract excerpt
Mutations in the transcription factors FOXP1 and FOXP2 are associated with speech impairments. FOXP1 is additionally linked to cognitive deficits, as is FOXP4. These FoxP proteins are highly conserved in vertebrates and expressed in comparable brain regions, including the striatum. In male zebra finches, experimental manipulation of FoxP2 in Area X, a striatal song nucleus essential for vocal production learning,...
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