Article

Comparative Multiomic Analysis Reveals Low T Cell Infiltration as the Primary Feature of Tobacco Use in HPV(+) Oropharyngeal Cancer

2021-03-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> Tobacco use is an independent adverse prognostic feature in human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC). Despite this, the biologic features associated with tobacco use have not been systematically investigated in this population. We sought to characterize the genomic and immunologic features of HPV(+) OPSCC associated with tobacco use an...

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Literature Corpus work: 35cdbad3-d427-5374-8759-5218b1c209f5
DOI: 10.1101/2021.03.23.436478

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