Article
Cerebellar zonal patterning relies on Purkinje cell neurotransmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 11 Jun 2014
White Joshua J, Arancillo Marife, Stay Trace L, George-Jones Nicholas A, Levy Sabrina L, Heck Detlef H, Sillitoe Roy V
Abstract excerpt
Cerebellar circuits are patterned into an array of topographic parasagittal domains called zones. The proper connectivity of zones is critical for motor coordination and motor learning, and in several neurological diseases cerebellar circuits degenerate in zonal patterns. Despite recent advances in understanding zone function, we still have a limited understanding of how zones are formed. Here, we focused our...
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